Table 3 Association of total calcium and vitamin D intake with prostate cancer in African Americans and European Americans
From: Race and BMI modify associations of calcium and vitamin D intake with prostate cancer
|  | Controls |  | Cases vs. Controls |  | High Risk vs. Controls |  | Gleason Score ≥4 + 3 vs. Controls | |||
|---|---|---|---|---|---|---|---|---|---|---|
Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | |||||
| Â | n (%) | n (%) | OR (95% C.I.) | OR (95% C.I.) | n (%) | OR (95% C.I.) | OR (95% C.I.) | n (%) | OR (95% C.I.) | OR (95% C.I.) |
Total Calcium, mg/day | ||||||||||
 African Americans | ||||||||||
  Quartile 1 (<368.8) | 143 (28.8) | 111 (28.4) | 1.00 | 1.00 | 25 (23.8) | 1.00 | 1.00 | 18 (21.7) | 1.00 | 1.00 |
  Quartile 2 (368.8–616.0) | 113 (22.7) | 90 (23.0) | 1.03 (0.71–1.49) | 0.94 (0.61–1.58) | 21 (20.0) | 1.06 (0.57–2.00) | 1.39 (0.63–3.09) | 17 (20.5) | 1.20 (0.59–2.42) | 1.47 (0.62–3.51) |
  Quartile 3 (616.1–1033.3) | 123 (24.7) | 91 (23.3) | 0.95 (0.66–1.38) | 1.20 (0.73–1.97) | 24 (22.9) | 1.12 (0.61–2.05) | 1.88 (0.81–4.37) | 23 (27.7) | 1.49 (0.77–2.88) | 2.32 (0.98–5.51) |
  Quartile 4 (>1033.3) | 118 (23.7) | 99 (25.3) | 1.08 (0.75–1.56) | 1.33 (0.78–2.26) | 35 (33.3) | 1.70 (0.96–3.00) | 4.28 (1.70–10.80) | 25 (30.1) | 1.68 (0.88–3.23) | 3.42 (1.30–9.00) |
  P for Trend |  |  | 0.73 | 0.28 |  | 0.05 | 0.001 |  | 0.10 | 0.01 |
 European Americans | ||||||||||
  Quartile 1 (<368.8) | 80 (21.2) | 54 (22.3) | 1.00 | 1.00 | 5 (14.3) | 1.00 | 1.00 | 9 (15.5) | 1.00 | 1.00 |
  Quartile 2 (368.8–616.0) | 115 (30.4) | 60 (24.8) | 0.77 (0.49–1.23) | 0.84 (0.50–1.40) | 10 (28.6) | 1.39 (0.46–4.23) | 1.66 (0.50–5.52) | 15 (25.9) | 1.16 (0.48–2.78) | 1.27 (0.50–3.22) |
  Quartile 3 (616.1–1033.3) | 87 (23.0) | 72 (29.8) | 1.23 (0.77–1.95) | 1.19 (0.70–2.03) | 8 (22.9) | 1.47 (0.46–4.68) | 1.63 (0.43–6.18) | 16 (27.6) | 1.64 (0.68–3.91) | 1.05 (0.41–2.68) |
  Quartile 4 (>1033.3) | 96 (25.4) | 56 (23.1) | 0.86 (0.54–1.39) | 0.81 (0.46–1.43) | 12 (34.3) | 2.00 (0.68–5.92) | 1.65 (0.44–6.16) | 18 (31.0) | 1.67 (0.71–3.91) | 1.23 (0.48–3.11) |
  P for Trend |  |  | 0.98 | 0.54 |  | 0.20 | 0.88 |  | 0.18 | 0.54 |
   P for Interaction (Total Calcium Intake x Race) |  |  |  | 0.70 |  |  | 0.99 |  |  | 0.99 |
Total Vitamin D, IU/day | ||||||||||
 African Americans | ||||||||||
  Quartile 1 (<63.5) | 120 (24.1) | 165 (23.6) | 1.00 | 1.00 | 29 (27.6) | 1.00 | 1.00 | 23 (27.7) | 1.00 | 1.00 |
  Quartile 2 (63.5–239.2) | 139 (28.0) | 170 (24.3) | 0.87 (0.61–1.25) | 0.83 (0.51–1.34) | 29 (27.6) | 0.86 (0.49–1.53) | 0.57 (0.26–1.24) | 22 (26.5) | 0.83 (0.44–1.56) | 0.54 (0.24–1.25) |
  Quartile 3 (239.3–510.2) | 135 (27.2) | 186 (26.6) | 0.80 (0.56–1.15) | 0.74 (0.45–1.21) | 37 (35.2) | 1.13 (0.66–1.96) | 0.58 (0.26–1.27) | 28 (33.7) | 1.08 (0.59–1.98) | 0.69 (0.31–1.55) |
  Quartile 4 (>510.2) | 103 (20.7) | 178 (25.5) | 0.71 (0.48–1.07) | 0.53 (0.30–0.94) | 10 (9.5) | 0.40 (0.19–0.86) | 0.06 (0.02–0.21) | 10 (12.0) | 0.51 (0.23–1.11) | 0.17 (0.06–0.54) |
  P for Trend |  |  | 0.11 | 0.03 |  | 0.05 | <0.001 |  | 0.18 | 0.008 |
 European Americans | ||||||||||
  Quartile 1 (<63.5) | 88 (23.3) | 56 (23.1) | 1.00 | 1.00 | 9 (25.7) | 1.00 | 1.00 | 12 (20.7) | 1.00 | 1.00 |
  Quartile 2 (63.5–239.2) | 81 (21.4) | 44 (18.2) | 0.85 (0.52–1.40) | 0.82 (0.47–1.44) | 3 (8.6) | 0.36 (0.10–1.38) | 0.24 (0.05–1.11) | 11 (19.0) | 1.00 (0.42–2.38) | 0.72 (0.27–1.93) |
  Quartile 3 (239.3–510.2) | 89 (23.5) | 57 (23.6) | 1.01 (0.63–1.61) | 1.09 (0.63–1.87) | 10 (28.6) | 1.10 (0.43–2.83) | 1.08 (0.34–3.44) | 14 (24.1) | 1.15 (0.51–2.63) | 1.05 (0.41–2.68) |
  Quartile 4 (>510.2) | 120 (31.7) | 85 (35.1) | 1.11 (0.72–1.72) | 1.25 (0.74–2.12) | 13 (37.1) | 1.06 (0.43–2.59) | 1.32 (0.40–4.33) | 21 (36.2) | 1.28 (0.60–2.75) | 1.23 (0.48–3.11) |
  P for Trend |  |  | 0.37 | 0.14 |  | 0.39 | 0.15 |  | 0.44 | 0.36 |
   P for Interaction (Total Vitamin D Intake x Race) |  |  |  | 0.23 |  |  | 0.007 |  |  | 0.14 |