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Table 1 Demographic characteristics of the patients

From: Microvascular invasion has limited clinical values in hepatocellular carcinoma patients at Barcelona Clinic Liver Cancer (BCLC) stages 0 or B

Features

Discovery cohort

(n = 1540)

Validation Cohort

(n = 630)

Age, median (range), year

53.0 (10–86)

53.0 (12–92)

Gender, male/female

1305 (84.7%)/235 (15.3%)

530 (84.1%)/100 (15.9%)

α-Fetoprotein (>200/≤200 ng/dL)

593 (38.5%)/947 (61.5%)

259 (41.1%)/371 (58.9%)

Liver cirrhosis, yes/no/unknown

1268 (82.3%)/251 (16.3%)/21 (1.4%)

512 (81.3%)/102 (16.2%)/16 (2.5%)

Hepatitis B history, yes/no/unknown

1255 (81.5%)/254 (16.5%)/31 (2.0%)

527 (83.7%)/94 (14.9%)/9 (1.4%)

Tumor size, mean ± SD, cm

5.3 ± 3.5

5.5 ± 3.7

Tumor number, multiple/solitary

199 (12.9%)/1341 (87.1%)

78 (12.4%)/552 (87.6%)

Types of resection, anatomic/non-anatomic

1222 (79.4%)/318 (20.6%)

475 (75.4%)/155 (24.6%)

Encapsulation, complete/none/unknown

733 (47.6%)/803 (52.1%)/4 (0.3%)

294 (46.7%)/335 (53.2%)/1 (0.2%)

Tumor differentiation, I–II/III–IV/unknown

1098 (71.3%)/421 (27.3%)/21 (1.4%)

441 (70.0%)/171 (27.1%)/18 (2.9%)

Microvascular invasion, yes/no

389 (25.3%)/1151 (74.7%)

205 (32.5%)/425 (67.5%)

BCLC stage, 0/A/B

194 (12.6%)/1192 (77.4%)/154 (10.0%)

87 (13.8%)/484 (76.8%)/59 (9.4%)