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Table 1 Demographic characteristics of the patients

From: Microvascular invasion has limited clinical values in hepatocellular carcinoma patients at Barcelona Clinic Liver Cancer (BCLC) stages 0 or B

Features Discovery cohort (n = 1540) Validation Cohort (n = 630)
Age, median (range), year 53.0 (10–86) 53.0 (12–92)
Gender, male/female 1305 (84.7%)/235 (15.3%) 530 (84.1%)/100 (15.9%)
α-Fetoprotein (>200/≤200 ng/dL) 593 (38.5%)/947 (61.5%) 259 (41.1%)/371 (58.9%)
Liver cirrhosis, yes/no/unknown 1268 (82.3%)/251 (16.3%)/21 (1.4%) 512 (81.3%)/102 (16.2%)/16 (2.5%)
Hepatitis B history, yes/no/unknown 1255 (81.5%)/254 (16.5%)/31 (2.0%) 527 (83.7%)/94 (14.9%)/9 (1.4%)
Tumor size, mean ± SD, cm 5.3 ± 3.5 5.5 ± 3.7
Tumor number, multiple/solitary 199 (12.9%)/1341 (87.1%) 78 (12.4%)/552 (87.6%)
Types of resection, anatomic/non-anatomic 1222 (79.4%)/318 (20.6%) 475 (75.4%)/155 (24.6%)
Encapsulation, complete/none/unknown 733 (47.6%)/803 (52.1%)/4 (0.3%) 294 (46.7%)/335 (53.2%)/1 (0.2%)
Tumor differentiation, I–II/III–IV/unknown 1098 (71.3%)/421 (27.3%)/21 (1.4%) 441 (70.0%)/171 (27.1%)/18 (2.9%)
Microvascular invasion, yes/no 389 (25.3%)/1151 (74.7%) 205 (32.5%)/425 (67.5%)
BCLC stage, 0/A/B 194 (12.6%)/1192 (77.4%)/154 (10.0%) 87 (13.8%)/484 (76.8%)/59 (9.4%)