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Table 1 Relationship characteristics of pediatric ALL and Bmi-1 expression level

From: Upregulation of the proto-oncogene Bmi-1 predicts a poor prognosis in pediatric acute lymphoblastic leukemia

Characteristics

n

Bmi-1

P value

Low expression

High expression

Age at diagnosis, y

   

0.100

  < 6

43

30 (69.8%)

13 (30.2%)

 

  ≥ 6

42

22 (52.4%)

20 (47.6%)

 

Gender

   

0.161

 Male

60

26 (43.3%)

34 (56.7%)

 

 Female

25

15 (60%)

10 (40%)

 

WBC count (×109/L)

   

0.153

  < 50

53

30 (56.6%)

23 (43.4%)

 

  ≥ 50

32

13 (40.6%)

19 (59.4%)

 

FAB classification

   

0.315a

 L1

34

13 (38.2%)

21 (61.8%)

 

 L2

47

26 (55.3%)

21 (44.6%)

 

 L3

4

2 (50%)

2 (50%)

 

Immunophenotype

   

0.281a

 T

11

4 (36.4%)

7 (63.6%)

 

 B

66

39 (59%)

27 (41%)

 

BCR/ABL

   

0.329a

 +

8

3 (37.5%)

5 (62.5%)

 

 -

64

40 (62.5%)

24 (37.5%)

 

Prednisone-test

   

0.039

 PGR

61

36 (59%)

25 (41%)

 

 PPR

14

4 (28.6%)

10 (71.4%)

 

Risk group

   

0.002a

 LR

16

14 (87.5%)

2 (12.5%)

 

 IR

31

16 (51.6%)

15 (48.4%)

 

 HR

31

10 (32.3%)

21 (67.7%)

 
  1. aTwo-sided Fisher’s exact test