Fig. 1

Bmi-1 expression was increased in the pediatric ALL clinical specimens. The qRT-PCR assay was repeated three times and produced similar results for each replicate. The Bmi-1 levels are presented as the means ± standard deviation (M ± SD) and were normalized to the GAPDH levels. a The average expression levels of Bmi-1 in pediatric ALL patients (n = 85) versus normal control subjects (n = 18). b The average expression levels of Bmi-1 before and after therapy (n = 19) in the paired samples from pediatric ALL patients. ***P < 0.001; *P < 0.05. CR, complete remission