Fig. 3From: Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosisAR-42 and SAHA treatment enhanced histone acetylation in both human and canine osteosarcoma cells. OS cells were treated with DMSO and the indicated concentrations of AR-42 or SAHA for 48 h. The acetylation status of histones H3 and H4 were determined by Western blotting. β-actin was used as a loading controlBack to article page