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Table 3 Association between DDR biomarkers and pCR in TNBC patients with BMI < 25 and BMI ≥ 25 (N = 54)

From: Body mass index modifies the relationship between γ-H2AX, a DNA damage biomarker, and pathological complete response in triple-negative breast cancer

 

BMI < 25

BMI ≥ 25

No pCR

pCR

Fisher’s Exact Test

No pCR

pCR

Fisher’s Exact Test

N (%)

N (%)

p-value

N (%)

N (%)

p-value

pCHK1

 Neg

4 (33.3)

8 (66.7)

0.022

4 (100.0)

0 (0.0)

0.539

 Pos

15 (78.9)

4 (21.1)

 

14 (73.7)

5 (26.3)

 

γ-H2AX

 low

6 (37.5)

10 (62.5)

0.009

7 (77.8)

2 (22.2)

0.999

 high

13 (86.7)

2 (13.3)

 

11 (78.6)

3 (21.4)

 
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BMC Cancer

ISSN: 1471-2407

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