Skip to main content

Table 4 Concordance of PIK3CA mutation status between endoscopic biopsy and surgically resected specimens

From: Concordance between PIK3CA mutations in endoscopic biopsy and surgically resected specimens of esophageal squamous cell carcinoma

  Surgically resected specimens (reference method)
Wild type Mutant type Total
Endoscopic biopsy specimens (trial method) Wild type 168 2 170
Mutant type 1 10 11
Total 169 12 181
Overall concordance rate 98.3% (95% CI: 95.2–99.7)
Positive concordance rate 83.3% (95% CI: 51.6–97.9)
Negative concordance rate 99.4% (95% CI: 96.7–99.9)
Positive predictive value 90.9% (95% CI: 58.7–99.8)
Negative predictive value 98.8% (95% CI: 95.8–99.9)
  1. Abbreviations: CI confidence interval