Fig. 6From: Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancerC57BL/6 mice tolerated the drugs well without signs of weight loss. a PB28; (b) PB221; (c) PB183; (d) F281; (e) PB282. Data represent Means ± SEM, n = 7–10 per group p < 0.0001Back to article page