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Table 4 Multivariate Cox regression analysis of independent factors influencing overall and disease free survival

From: Detection of circulating tumor cells with CK20 RT-PCR is an independent negative prognostic marker in colon cancer patients – a prospective study

Factor

Category

Hazard ratio

95% CI

P value

Overall survival

 CK20 blooda

positive vs. negative

1.94

1.0–3.7

0.042

 Age [years]

<70 vs. >70

2.7

1.4–5.4

0.004

 pN stage

pN0 vs. pN1/2

0.7

0.2–2.7

0.62

 pT stage

pT1/2 vs. pT3/4

3.3

1.3–8.4

0.015

 UICC stage

I + II vs. III + IV

6.4

1.6–26.3

0.01

Disease free survival

 CK20 blooda

positive vs. negative

1.94

1.1–3.7

0.044

 pN stage

pN0 vs. pN1/2

1.39

0.3–5.8

0.65

 pT stage

pT1/2 vs. pT3/4

2.88

1.1–7.5

0.03

 UICC stage

I + II vs. III + IV

4.9

1.0–23.7

0.045

  1. Abbreviation: CI confidence interval
  2. aTumor cell detection with CK20 RT-PCR
  3. The data in bold are regarded statistically significant (p < 0.05)