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Table 3 Number of patients with pan-cytokeratin or EpCAM positive tumor cells in the bone marrow detected with immunohistochemistry and association with patients’ characteristics (crosstabs, chi-square test, two sided)

From: Detection of circulating tumor cells with CK20 RT-PCR is an independent negative prognostic marker in colon cancer patients – a prospective study

Characteristics Category pan-cytokeratin Detection rate (%) P EpCAM Detection rate (%) P
All   30 (134) 22.3 - 12 (61) 19.7 -
UICC stage I 6 (30) 20.0 0.335 2 (8) 25.0 0.587
II 7 (40) 17.5   2 (14) 14.2  
III 8 (39) 20.5   3 (22) 13.6  
IV 9 (25) 36.0   5 (17) 29.4  
pT T1 4 (16) 25.0 0.861 2 (5) 40.0 0.575
T2 4 (25) 16.0   1 (10) 10.0  
T3 17 (5) 29.4   7 (34) 20.6  
T4 5 (22) 22.7   2 (12) 16.4  
pN N0 14 (75) 18.6 0.324 5 (24) 20.8 0.253
N1 8 (35) 22.8   2 (21) 9.5  
N2 8 (24) 33.3   5 (16) 31.2  
Grading G1 1 (9) 11.1 0.702 0 (3) 0 0.108
G2 23 (99) 23.23   12 (47) 25.5  
G3 6 (26) 23.1   0 (11) 0  
Liver M0 21 (104) 20.1 0.07 7 (44) 15.9 0.287
Metastases M1 9 (30) 30   5 (17) 29.4  
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