Fig. 6

Effect of BT-cisplatin combination on ATX secretion in ovarian cancer cell lines. A2780 and A2780-CDDP (a) or IGROV-1 and IGROV-1-CDDP (b) cells were treated with drugs either alone or in combination and ATX was measured from culture media (via a colorimetric assay). The percent of ATX inhibition of treated cells was calculated using untreated cells as reference. Data were expressed as means ± SD of triplicate experiments. Comparisons between cisplatin alone-treated and combination-treated for each cell line were performed using Student’s t–test. Asterisks (*) indicate p < 0.05