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Table 2 Association of CUBN positivity with clinicopathological parameters in ccRCC

From: A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

Variable

Cohort 2

Cohort 3

N

CUBN negative

N (%)

CUBN positive

N (%)

P-value

N

CUBN negative

N (%)

CUBN positive

N (%)

P-value

Spread at diagnosis

131

   

114

   

 Local

 

50 (96)

72 (91)

  

15 (33)

39 (57)

 

 Metastatic

 

2 (4)

7 (9)

0.317b

 

31 (67)

29 (43)

0.009a

T-Stage

123

    

 T1-T2

 

5 (10)

14 (19)

 

n.a.

 T3-T4

 

45 (90)

59 (81)

0.167a

 

Fuhrman Grade

95

    

 1–2

 

8 (23)

31 (52)

 

n.a.

 3–4

 

27 (77)

29 (48)

0.006a

 

Nodal Status

131

    

 Negative

 

39 (75)

73 (92)

 

n.a.

 Positive

 

13 (25)

6 (8)

0.006a

 
  1. N number of patients
  2. aχ2 test
  3. bFisher’s exact test; n.a., not available
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BMC Cancer

ISSN: 1471-2407

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