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Table 1 CUBN positivity rates on multi-cancer TMA cohort (Cohort 1)

From: A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

Cancer origin

N (912 total)

CUBN positive N (%a)

Prostate

57

0 (0)

Colon

59

0 (0)

Breast

60

0 (0)

Stomach

59

0 (0)

Lung

105

0 (0)

Ovary

60

0 (0)

Endometrium

59

0 (0)

Cervix

59

0 (0)

Hepatocellular

28

0 (0)

Neuroendocrine

30

0 (0)

Sarcoma

60

0 (0)

Urothelial

20

0 (0)

Renal cell carc.

39

22 (56)

 - ccRCC

30

18 (60)

 - other

9

4 (44)

Lymphoma

20

0 (0)

Melanoma

20

0 (0)

Testis

18

0 (0)

Oesophagus

22

0 (0)

Thyroid

18

0 (0)

Head and Neck

20

1 (5)

Pancreas

51

0 (0)

Cholangiocarc.

41

0 (0)

Gall bladder carc.

7

0 (0)

CUBN specificityb

 

100%

CUBN PPVb

 

96%

  1. N number of patients, ccRCC clear cell renal cell carcinoma
  2. aPercentage of positive cases within tumor type
  3. bFor RCC compared to all other cases; PPV, positive predictive value