Fig. 9From: PGE2 promotes breast cancer-associated lymphangiogenesis by activation of EP4 receptor on lymphatic endothelial cellsExpression of angiogenesis and lymphangiogenesis markers in angioreactors obtained at DIVLA a. Macroscopic images of angioreactors collected with surrounding tissues. b Quantitative real-time PCR analysis of Lyve1 Prox-1 and CD31 mRNA expression in the cellular contents of angioreactors. Expression levels are normalized to actin. c relative fluorescence analysis of Lyve1, Prox1, and CD31 proteins as expressed by mouse lymphatic and blood vascular endothelial cells recruited into the angioreactors. Data are presented as mean ± SEM. (*) indicates significant difference p < 0.05 and (**) indicates p < 0.001Back to article page