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Fig. 7 | BMC Cancer

Fig. 7

From: PGE2 promotes breast cancer-associated lymphangiogenesis by activation of EP4 receptor on lymphatic endothelial cells

Fig. 7

Effects of PI3K/Akt and Erk inhibitors on tube formation by RMLEC. a Representative photo-micrographs of RMLEC tubular network formation in response to PGE2 and PGE1OH in presence of PI3K/Akt inhibitors (Ly294002 and wortmanin) or Erk inhibitor (U0126). Bars equal 100 μm. b Quantification of branch points of tubular structures corresponding to (a) as determined by ImageJ. (***) represents p = 0.0001

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