The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases

Table 3 Neurocognitive and quality of life assessment compliance

Evaluation Status	RCT arm		RT arm		P
Evaluation Status	Not evaluated	Received	Not evaluated	Received
Hopkins Verbal Learning Test (HVLT-R)
Baseline	5	124	4	105	0.93
At 3 Months	24	105	32	87	0.12
At 5 Months	57	72	55	64	0.75
At 7 Months	87	42	83	36	0.70
Trail-making Test (TMT)
Baseline	6	123	4	105	0.71
At 3 Months	26	103	31	88	0.27
At 5 Months	59	70	57	62	0.73
At 7 Months	85	44	83	36	0.52
Controlled Oral Word Association (COWA) test
Baseline	5	124	6	103	0.55
At 3 Months	24	105	30	89	0.21
At 5 Months	57	72	58	61	0.47
At 7 Months	85	44	85	34	0.35
Functional Assessment of Cancer Treatment-Lung (FACT-L)
Baseline	7	122	9	100	0.48
At 3 Months	27	102	34	85	0.16
At 5 Months	56	73	54	65	0.76
At 7 Months	88	41	86	33	0.49

Abbreviations: Hopkins Verbal Learning Test HVLT-R, Trail-making Test TMT, Controlled Oral Word Association test COWA, Functional Assessment of Cancer Treatment-Lung FACT-L

ISSN: 1471-2407