Fig. 3
Differential relative stability of miRNAs and RNU6B snRNA in FFPE samples stored for long periods of time. Linear associations between miRNA SQ mean levels, or RNU6B SQ Mean levels, and FFPE Sample Age were analyzed and compared. a RNU6B and miR-21 had similar stabilities over 12–20 years (p-interaction = 0.194, p = 0.178 by analysis of covariance). b miR-141 was significantly more stable than RNU6B snRNA over 12–20 years (p-interaction = 1.9 × 10−8). c miR-221 was significantly more stable than RNU6B snRNA over 12–20 years (p-interaction = 2.0 × 10−16). d miR-221 was significantly more stable than miR-21 (p = 5.0 × 10−14) and miR-141 was significantly more stable than miR-21 (p = 2.8 × 10−8) over 12–20 years