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Table 1 Distribution of TOP1 CN and ratios for the 108 patients

From: Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer

 

TOP1 CN No (%)

TOP1/CEN-2 ratio No (%)

TOP1/CEN-20 ratio No (%)

<2

7 (6)

50 (46)

98 (91)

2.0 – 2.99

23 (21)

36 (33)

10 (9)

3.0 – 3.99

14 (13)

18 (17)

-

4.0 – 4.99

25 (23)

3 (3)

-

5.0 – 5.99

15 (14)

-

-

6.0 – 6.99

13 (12)

1 (1)

-

>7

11 (10)

-

-