Skip to main content

Table 5 Performance and internal validation of all the multivariate cox proportional hazard models

From: Prognostic values of EORTC QLQ-C30 and QLQ-HCC18 index-scores in patients with hepatocellular carcinoma – clinical application of health-related quality-of-life data

MV model c-index 95% CI Mean c-index from 1000 bootstraps 95% CI based on 1000 bootstrap samples Optimism Optimism in %
M1 0.7872 0.7648–0.8095 0.7891 0.7678–0.8111 0.0019 0.24%
M2 0.7842 0.7617–0.8066 0.7878 0.7660–0.8103 0.0036 0.46%
M3 0.7817 0.7591–0.8043 0.7840 0.7626–0.8066 0.0023 0.29%
M4 0.7810 0.7588–0.8032 0.7841 0.7638–0.8056 0.0031 0.40%
M5 0.7821 0.7598–0.8043 0.7839 0.7621–0.8072 0.0018 0.23%
M6 0.7791 0.7564–0.8018 0.7715 0.7604–0.8034 −0.0076 −0.96%
  1. MV multivariate, CI confidence interval
  2. M1: the multivariate cox model using QLQ-C30 as continuous variables
  3. M2: the multivariate cox model using QLQ-C30 as dichotomized variables
  4. M3: the multivariate cox model using C30 index score
  5. M4: the multivariate cox model using QLQ-HCC18 as continuous variables
  6. M5: the multivariate cox model using QLQ-HCC18 as dichotomized variables
  7. M6: the multivariate cox model using HCC18 index score