Skip to main content

Table 2 Univariate analysis of intracerebral control

From: A matched-pair study comparing whole-brain irradiation alone to radiosurgery or fractionated stereotactic radiotherapy alone in patients irradiated for up to three brain metastases

 

At 1 year (%)

At 2 years (%)

At 3 years (%)

P

Type of irradiation

 WBI alone

40

15

15

 

 RS/FSRT alone

45

22

17

0.84

Age

  ≤ 60 years

45

20

17

 

  > 60 years

43

16

16

0.51

Gender

 Female

44

21

18

 

 Male

42

15

n.a.

0.47

ECOG performance score

 0–1

44

23

20

 

 2

42

0

0

0.05

Nature of tumor

 Breast cancer

58

28

28

 

 Non-small-cell lung cancer

46

19

19

 

 Small-cell lung cancer

50

n.a.

n.a.

 

 Kidney cancer

39

20

20

 

 Melanoma

24

9

0

 

 Cancer of unknown primary

47

0

0

 

 Gastrointestinal cancers

0

0

0

 

 Gynecological cancers

0

0

0

0.014

Brain metastases number

 1

50

26

26

 

 2–3

33

10

8

<0.001

Extra-cerebral spread

 No

44

18

18

 

 Yes

43

21

14

0.27

Period from cancer detection to irradiation

  ≤ 15 months

36

10

10

 

  > 15 months

50

26

22

0.05

RPA-class

 1

45

21

21

 

 2

42

17

11

0.07

  1. n.a. not available; according to Bonferroni correction, p-values <0.0056 were considered significant