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Table 2 Inhibition of HeLa cell proliferation by DDP

From: Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells

DDP concentration (μmol/L)

I (24 h)

II (48 h)

III (72 h)

IV (96 h)

0

0

0

0

0

0.5a

5.27 ± 0.41

11.30 ± 1.02f

19.79 ± 0.92g

26.19 ± 0.63h

1b

8.94 ± 0.76

19.39 ± 0.88f

49.57 ± 1.08g

68.26 ± 1.31h

2c

12.17 ± 0.28

39.24 ± 0.72f

72.32 ± 0.67g

79.55 ± 0.22

5d

14.33 ± 0.69

68.26 ± 1.00f

81.95 ± 1.34g

85.03 ± 1.11

10e

31.57 ± 2.01

71.93 ± 0.33f

87.46 ± 0.86g

92.54 ± 0.92

20

37.85 ± 0.78

79.19 ± 1.12f

89.50 ± 1.13g

95.36 ± 0.48

IC50

46.30 ± 0.27

3.68 ± 0.16

1.24 ± 0.89

0.76 ± 0.05

  1. a P < 0.05;b P < 0.05;c P < 0.05;d P < 0.05;e P < 0.05; f P < 0.05;g P < 0.05; h P <0.05