Fig. 7
From: Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells
Immunohistochemistry staining for ST6Gal-I and BCL-2 protein in xenograft tumor model. Cytoplasmic staining was considered to be positive for ST6Gal-I and BCL-2. (A) + (B) matched samples with accentuated BCL-2 protein expression and (a) + (b) matched samples with strong positive ST6Gal-I expression for the control group (staining intensity 3). (C) + (D) matched samples with moderate BCL-2 protein expression and (c) + (d) matched samples with weaker positive ST6Gal-I expression for the NC-shRNA HeLa cells group (staining intensity 2). (E) + (F) matched samples with weakest positive BCL-2 expression and (e) + (f) matched samples with almost complete loss of ST6Gal-I protein for the ST6Gal-I-shRNA HeLa cells group (staining intensity 1). (G) Positive control: breast cancer sample with strong ST6Gal-I staining (staining intensity 3). (H) Negative control: breast cancer sample with no staining (staining intensity 0). A, C, E, G, H, a, c and e show 100 × amplification in the light microscope. B, D, F, b, d, and f show 400 × amplification in the light microscope