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Fig. 2 | BMC Cancer

Fig. 2

From: Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

Fig. 2

PDE inhibitor induced increase in SCC. Rolipram gave a significantly larger inhibition in CTRL- compared to CRN-patients, whereas, sildenafil and cilostamide showed no significant difference. Control patients: rolipram 12.7 ± 1.4 (N = 11, n = 11), sildenafil 6.6 ± 1.2 (N = 9, n = 9) cilostamide 64.9 ± 3.0 (N = 11, n = 13). Neoplasia patients: rolipram 8.1 ± 0.7 (N = 10, n = 10), sildenafil 6.4 ± 0.8 (N = 8, n = 8), cilostamide 61.9 ± 5.1 (N = 11, n = 12). Changes presented as mean SCC ± SEM. * Indicates a statistical difference. *p < 0.05

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BMC Cancer

ISSN: 1471-2407

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