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Fig. 4 | BMC Cancer

Fig. 4

From: Agonists and knockdown of estrogen receptor β differentially affect invasion of triple-negative breast cancer cells in vitro

Fig. 4

Network of genes regulated after ERβ knockdown in MDA-MB-231 cells and cellular location of their gene products. In DNA microarray analyses, the indicated genes were found to be induced more than 2-fold (p < 0.05) after ERβ knockdown, except the two genes marked with a black arrow, which were down regulated at least 2-fold. * = protein with function in extracellular matrix. Dashed line: association of undefined type due to co-citation of gene A and B; solid line with arrow: activation of gene B by gene A; solid line with rhombus: modulation of gene B by gene A. This figure was created using Genomatix Pathway Analysis software (Genomatix, Munich, Germany)

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