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Table 5 Pairwise comparison of the recommendations from the index MDT versus ESMO and NCCN guidelines

From: Computational prediction of multidisciplinary team decision-making for adjuvant breast cancer drug therapies: a machine learning approach

Treatment Modality

Agreement between the expertise

Strategy

MDT versus ESMO

MDT versus NCCN

ESMO versus NCCN

 

N

(%)

N

(%)

N

(%)

Chemotherapy

 Overalla

551/975

(57)

462/975

(47)

320/1065

(30)

 Aggressive

628/975

(64)

616/975

(63)

416/1065

(39)

 Conservative

729/975

(75)

731/975

(75)

721/1065

(68)

Endocrine therapy

 Overalla

853/1002

(85)

840/1002

(84)

976/1065

(92)

 Aggressive

970/1002

(97)

953/1002

(95)

1024/1065

(96)

 Conservative

858/1002

(86)

861/1002

(86)

976/1065

(92)

Trastuzumab

 Overalla

437/456

(96)

437/456

(96)

1047/1065

(98)

 Aggressive

444/456

(97)

446/456

(98)

1058/1065

(99)

 Conservative

437/456

(98)

440/456

(97)

1047/1065

(98)

  1. Abbreviations: MDT multidisciplinary team meeting, ESMO European Society for Medical Oncology guideline, NCCN National Comprehensive Cancer Network guideline
  2. aOverall – three-way grouping of “Recommended”, “For discussion”, “Not recommended”