Demographics
|
Age group (years)
|
<45
|
141
|
(13)
|
| |
45-55
|
242
|
(23)
|
| |
56-69
|
393
|
(37)
|
| |
≥70
|
266
|
(25)
|
Surgery type
|
Primary tumour
|
WLE or partial mastectomy
|
608
|
(57)
|
| |
Total mastectomy
|
452
|
(42)
|
|
Lymph node
|
Sentinel node biopsy only
|
703
|
(66)
|
| |
Axillary lymph node dissection
|
255
|
(24)
|
Nodal status
|
Sentinel lymph node
|
Involved
|
269
|
(25)
|
| |
Not involved
|
590
|
(55)
|
|
Axillary lymph nodes involved
|
No
|
625
|
(59)
|
| |
1-3
|
240
|
(23)
|
| |
≥4
|
108
|
(11)
|
|
Extranodal spread
|
Present
|
140
|
(13)
|
Histopathology
|
Cell type
|
Invasive ductal carcinoma
|
818
|
(77)
|
| |
Invasive lobular carcinoma
|
135
|
(13)
|
| |
Tubular carcinoma
|
27
|
(3)
|
| |
Mucinous carcinoma
|
12
|
(1)
|
| |
Medullary carcinoma
|
8
|
(0.8)
|
| |
Mixed type
|
8
|
(0.8)
|
| |
Basal type
|
7
|
(0.7)
|
| |
Metaplastic carcinoma
|
7
|
(0.7)
|
| |
Other malignant tumour
|
42
|
(4)
|
|
Multifocal
|
Multifocal
|
83
|
(9)
|
| |
Satellite lesions
|
66
|
(6)
|
|
Primary tumour size (cm)
|
≤0.5 (T1a)
|
42
|
(4)
|
| |
0.6-1.0 (T1b)
|
149
|
(14)
|
| |
1.1-2.0 (T1c)
|
423
|
(40)
|
| |
2.1-5.0 (T2)
|
347
|
(33)
|
| |
>5.0 (T3)
|
79
|
(7)
|
|
Histological grade
|
Grade 1
|
172
|
(12)
|
| |
Grade 2
|
445
|
(42)
|
| |
Grade 3
|
418
|
(39)
|
|
Lymphovascular invasion
|
Present
|
356
|
(33)
|
| |
Absent
|
308
|
(29)
|
|
Perineural invasion
|
Present
|
40
|
(4)
|
| |
Absent
|
111
|
(10)
|
|
Oestrogen receptor (ER) status
|
Positive
|
927
|
(87)
|
| |
Negative
|
135
|
(13)
|
|
Progesterone receptor (PR) status
|
Positive
|
843
|
(79)
|
| |
Negative
|
210
|
(20)
|
|
HER2 statusa
|
Positive
|
128
|
(12)
|
| |
Negative
|
654
|
(61)
|
|
Basal Type
|
Yes
|
31
|
(3)
|
|
Cytokeratin 5/6
|
Positive
|
59
|
(6)
|
|
Ki-67 (%)
|
<5%
|
94
|
(9)
|
| |
5-9%
|
130
|
(12)
|
| |
10-29%
|
231
|
(22)
|
| |
≥30%
|
153
|
(14)
|
Associated lesions
|
Second primary
|
Present
|
31
|
(3)
|
|
Ductal carcinoma in situ
|
High Grade
|
335
|
(32)
|
| |
Intermediate Grade
|
196
|
(18)
|
| |
Low grade
|
43
|
(4)
|
| |
Extensive
|
346
|
(33)
|
| |
Focal
|
318
|
(30)
|
|
Lobular carcinoma in situ
|
Focal
|
89
|
(8)
|
| |
Extensive
|
60
|
(6)
|
|
Other benign lesion(s)
|
Present
|
95
|
(9)
|