Fig. 5
From: Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells
SSTR1 cell signaling limits sphere formation and cell proliferation of ALDH positive cells. ALDH positive cells were cultured in low attachment dishes for colonosphere assay under various conditions with or without exogenous SST for HT29 (a and c) and SW480 (b and d) cells. These experiments were all done in duplicate, * p ≤ 0.05. SST = Somatostatin and CycloSST = Cyclosomatostatin