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Fig. 4 | BMC Cancer

Fig. 4

From: Keratin 19 as a key molecule in progression of human hepatocellular carcinomas through invasion and angiogenesis

Fig. 4

Immunohistochemical analysis of human HCC specimens. a Double immunostaining for K19 (cytoplasm, brown) and E-cadherin (membrane, red) showed that the percentage of cells positive for E-cadherin in K19-positive areas was lower than that in K19-negative areas of K19-positive HCC specimens. b Mirror image analysis of K19 and Ki-67 indicated Ki-67 proliferative index was higher in K19-positive areas than in K19-negative areas of K19-positive HCC specimens. c K19-positive HCC specimens had more CD31-positive blood vessels around cancer foci than did K19-negative HCC specimens. Original magnifications: ×400 (a, left), ×200 (a, right), ×100 b, c

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