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Table 1 IC50 Values of 11 cell lines using Trial Drug (DAAD2)

From: Synthesis and bio-molecular study of (+)-N-Acetyl-α-amino acid dehydroabietylamine derivative for the selective therapy of hepatocellular carcinoma

Cell Lines

IC50 Value of DAAD2

(μM conc.)

R2

Hep3B

2.0 ± 0.4

0.9

MCF7

2.2 ± 0.8

0.8

PLC

2.8 ± 0.6

0.9

Hep3B-TR

3.2 ± 0.8

0.8

Hep40

3.5 ± 1

0.8

SNU387

3.6 ± 0.6

0.8

SNU475

4.4 ± 0.6

0.7

Mahlavu

5.2 ± 0.9

0.6

Huh7

6.4 ± 2

0.6

HepG2

7.6 ± 0.8

0.5

SNU449

27.5 ± 5

0.7