Table 1 Patient characteristics

Age

Median (range)

57 (29–77)

-

Gender

Male

14

66.7

Female

7

33.3

ECOG PS

0

19

90.5

1

2

9.5

Primary site

Small intestine

10

47.6

Stomach

7

33.3

Others

4

19.0

Site of metastasis

Liver

20

95.2

Peritoneum

10

47.6

Lymph node

6

28.6

Others

2

9.5

Number of metastases

0

1

4.8

1–2

15

71.4

≥3

5

23.8

Target lesion

Yes

21

100

Previous surgery

Yes

14

66.7

Number of previous chemotherapy

Median (range)

3 (2–5)

-

Previous treatment

Imatinib

21

100

Sunitinib

20

95.2

Regorafenib

9

42.9

Interval from first line chemotherapy to starting for phase I trials

Median (years)

4.5 (1.4–10.1)

-

Number of enrolled phase I trials

1

12

57.1

≥2

9

42.9

Type of phase I trials

Targeting agents^a

19

90.5

Cytotoxic agents

1

4.8

Targeting and cytotoxic agents

1

4.8