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Fig. 1 | BMC Cancer

Fig. 1

From: Global DNA methylation profiling uncovers distinct methylation patterns of protocadherin alpha4 in metastatic and non-metastatic rhabdomyosarcoma

Fig. 1

A heatmap of DMRs associated to PCDHs genes. The heatmap shows the DNA methylation patterns of protocadherin loci (measured as log2 ratio of methylated dsDNA/ total genomic DNA) for the RMS samples analyzed. Each column represents the profile of a specific RMS sample, and each row represents the differentially methylated regions (DMRs) associated to PCDHs genes identified with iChip algorithm by comparing metastatic and non-metastatic samples. The enrichment value, expressed as moderated t-statistics extracted using the eBayes function, is associated to each DMR as result of iChip analysis. A positive enrichment value indicates hypermethylation in metastatic vs non-metastatic samples

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