Table 1 Data analysis of included studies
Study | N | Male | Female | Age (average) | Sources of tumor (N) | Volume of MPE (N) | Quality of Life | End point | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
Lung/pleura | Breast | Digestive tract | Others | ||||||||
Liu W 2010 [15] | 96 | 51 | 45 | 40–70 | 96 | – | – | – | Unavailable | KPS | RR, DCR, SI, AEs |
Mao L 2011 [16] | 90 | 45 | 45 | 27–70 | 81 | 5 | 2 | 2 | >1000 ml | KPS | RR, DCR, SI, AEs |
Li G 2011 [17] | 60 | 30 | 30 | 41–76 | 25 | 20 | 15 | – | Large (37) Moderate (23) | KPS | RR, DCR, SI, AEs |
Ma E 2012 [18] | 56 | 32 | 24 | 35–67 | 56 | – | – | – | >1000 ml | Unavailable | RR, DCR, SI, AEs |
Yao Q 2012 [19] | 60 | 42 | 18 | 35–78 | 28 | 16 | 4 | 12 | >1000 ml | KPS | RR, DCR, SI, AEs |
Zheng Q 2013 [20] | 120 | 73 | 47 | 32–75 | 78 | 25 | 17 | – | >1000 ml | KPS | RR, DCR, SI, AEs |
Kang Y 2013 [21] | 90 | 53 | 37 | 18–72 | 90 | – | – | – | >1000 ml | KPS | RR, DCR, SI, AEs |
Wen J 2014 [22] | 60 | 34 | 26 | 35–65 (50.5) | 45 | 9 | 6 | – | Large (13) Moderate (29) Small (18) | KPS | RR, DCR, SI, AEs |
Yue G 2014 [23] | 86 | 48 | 42 | 38–69 | 86 | – | – | – | Unavailable | KPS | RR, DCR, SI, AEs |
Tu J 2014 [24] | 90 | 41 | 49 | 45–70 | 90 | – | – | – | Unavailable | KPS | RR, DCR, SI, AEs |
Xu J 2014 [25] | 70 | 43 | 27 | 44–70 | 70 | – | – | – | >1000 ml | KPS | RR, DCR, SI, AEs |
Wen X 2015 [26] | 104 | 69 | 35 | 39–76 | 104 | – | – | – | Unavailable | KPS | RR, DCR, SI, AEs |
Hu X 2015 [27] | 84 | 62 | 22 | 18–70 | 69 | 3 | 12 | – | >1000 ml | ECOG | RR, DCR, SI, AEs |