Skip to main content

Table 1 Measures of agreement between OCR-based and POGONIS-based diagnostic groups

From: The validity of pediatric cancer diagnoses in a population-based general cancer registry in Ontario, Canada

Malignancy type N, POGONIS N, OCR Kappa (95 % CI) Sensitivity Specificity PPV NPV
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases 1305 1143 0.89 (0.88–0.91) 0.87 1.00 0.99 0.94
II. Lymphomas and reticuloendothelial neoplasms 585 554 0.90 (0.88–0.92) 0.89 0.99 0.94 0.98
III. CNS and miscellaneous intracranial and intraspinal neoplasms 790 757 0.95 (0.94–0.96) 0.94 1.00 0.98 0.99
IV. Neuroblastoma and other peripheral nervous cell tumors 262 256 0.97 (0.96–0.99) 0.96 1.00 0.98 1.00
V. Retinoblastoma 105 105 1.00 (1.00–1.00) 1.00 1.00 1.00 1.00
VI. Renal tumors 174 175 0.98 (0.96–0.99) 0.98 1.00 0.98 1.00
VII. Hepatic tumors 68 64 0.92 (0.88–0.97) 0.90 1.00 0.95 1.00
VIII. Malignant bone tumors 181 192 0.89 (0.86–0.92) 0.92 0.99 0.87 1.00
IX. Soft tissue and other extraosseus sarcomas 285 260 0.86 (0.82–0.89) 0.82 0.99 0.91 0.99
X. Germ cell tumors, trophoblastic tumors, and neoplasms of gonads 140 136 0.96 (0.93–0.98) 0.94 1.00 0.97 1.00
XI. Other malignant epithelial neoplasms and malignant melanomas 155 172 0.93 (0.90–0.96) 0.98 0.99 0.88 1.00
XII. Other and unspecified malignant neoplasms 23 259 0.06 (0.02–0.10) 0.43 0.94 0.04 1.00
  1. CI confidence interval, CNS central nervous system, N number, NPV negative predictive value, OCR Ontario Cancer Registry, POGONIS Pediatric Oncology Group of Ontario Networked Information System, PPV positive predictive value