Table 2 Correlation analysis of the expression of wtERa, ERa36 and ER-beta with clinical features (cohort P)
From: Alternative splicing of estrogen receptor alpha in hepatocellular carcinoma
Clinical features | Pearson correlation analysis | ||
|---|---|---|---|
Correlation coefficient | P valuea | ||
wtERa | Gender (Female vs. Male) | 0.662 | 0.000 |
Age (>58 vs. ≤58) | 0.276 | 0.007 | |
International Normalized Ratio | −0.442 | 0.000 | |
Size of the largest tumor (>5 cm vs. ≤5 cm) | −0.306 | 0.003 | |
Intra-hepatic recurrence (Yes vs. No) | −0.308 | 0.003 | |
Extra-hepatic metastasis (Yes vs. No) | −0.310 | 0.002 | |
Adjuvant treatments after operation (Yes vs. No) | −0.348 | 0.001 | |
ERa36 | Non-tumour liver (Cirrhosis vs. Fibrosis vs. Normal) | 0.270 | 0.009 |
Extra-hepatic metastasis (Yes vs. No) | −0.274 | 0.007 | |
Pathological Grade (Poor vs. Moderate vs. Well) | −0.274 | 0.007 | |
Liver cirrhosis (Yes vs. No) | 0.267 | 0.009 | |
ERb | Gender (Female vs. Male) | 0.234 | 0.023 |
Age (>58 vs. ≤58) | 0.308 | 0.002 | |
International Normalized Ratio | −0.273 | 0.009 | |
HBsAg (+ vs. -) | −0.377 | 0.000 | |