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Table 2 Proposed geriatric interventions defined in protocol according to the eleven areas and screening tools used

From: Role of geriatric intervention in the treatment of older patients with cancer: rationale and design of a phase III multicenter trial

Area

Indication

Intervention

Modification of therapy

Polypharmacy

• Re-evaluate treatment indications (with general practitioner), optimize treatment according to elderly patient protocols.

• Use the STOPP-START* tool as a reference [37, 38].

Balancing chronic diseases

CIRS-G* Grade ≥ 3,

• Adaptation of therapy.

arterial hypertension, diabetes, arthritis, or sensory problems

• Other non-drug interventions such as dietary advice, devices.

• Referral to specialist doctor.

Pain treatment

Pain >1 on numeric scale

• Drug: WHO levels 1–3 antalgic treatment

• Non-drug: physiotherapy, devices

Nutritional intervention

Malnutrition (MNA* ≤ 17)

• Referral to dietician (nutritional supplements, artificial nutrition, etc.)

Weight loss ≥5 % over 3 m, or ≥10 % over 6 m

At risk of malnutrition - 17 < MNA ≤ 23.5

• Advice on increasing dietary uptake (use of food pyramid adapted for elderly patients)

Physical activity

Sedentary or at risk of falls

• Recommend daily walk, walking upstairs, carrying groceries

Physiotherapy

Difficulty with walking and balance (TUG*, and SPPB*). Fall in the last 12 m, weight loss, muscle loss

• Prescribe physiotherapy for muscular reinforcement Work on balance, and getting up from lying down position

• Prescribe walking aids

Psychological support

GDS* ≥ 6

• Consultation with psychologist or psychiatrist

Apparent anxiety (clinical assessment)

Antecedent of depression

Prevention of further cognitive impairment

MMSE* < 24

• Behavioral monitoring during chemotherapy

• Prevention of confusion [39]

Treatment for sleeping disorders

Positive screening score on adapted Epworth scale [40]

• Introduction, modification or discontinuation of treatment by hypnosis according to STOPP and START recommendations [37, 38]

Assistance

Social fragility identified (absence of social support)

• Ask patient directly if help is needed

• Refer to a social worker

Home help

Difficulties performing daily tasks such as grooming, housework

• Prescribe support within the home (nursing, physiotherapy, housecleaner, etc.)

  1. *STOPP-START Screening Tool of Older persons’ prescriptions, CIRS-G Cumulative Illness Rating Scale for Geriatrics, MNA Mini Nutritional Assessment, TUG Timed Up and Go, SPPB Short Performance Physical battery, GDS Geriatric Depression Scale, MMSE Mini mental state examination