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Table 3 Hazard ratios for developing cancer in patients with CHI

From: Chronic hepatitis infection is associated with extrahepatic cancer development: a nationwide population-based study in Taiwan

 

HBV

HCV

No

Yes

 

No

Yes

 

Cancer type

Cases

Cases

HR

(95 % CI)a

Cases

Cases

HR

(95 % CI)a

Overall

2,139

1,330

2.67

(2.49–2.86)

1,893

1,232

2.83

(2.63–3.05)

Brain cancer

30

7

1.04

(0.45–2.39)

18

7

1.67

(0.68–4.15)

Head and neck cancer

288

66

0.96

(0.73–1.26)

171

48

1.13

(0.81–1.57)

Thyroid gland cancer

61

24

1.50

(0.93–2.42)

44

13

1.18

(0.62–2.24)

Esophageal cancer

54

15

1.42

(0.79–2.54)

46

11

1.24

(0.63–2.43)

Stomach cancer

132

32

1.11

(0.75–1.65)

122

37

1.41

(0.96–2.06)

Colorectal cancer

341

104

1.36

(1.09–1.70)

327

83

1.07

(0.84–1.38)

Liver cancer

155

770

1.47

(18.0–25.6)

137

782

25.10

(20.9–30.2)

Gallbladder and extrahepatic bile duct cancer

30

14

2.05

(1.07–3.91)*

32

18

2.60

(1.42–4.73)

Pancreatic cancer

35

19

2.61

(1.47–4.61)

55

17

1.51

(0.86–2.65)

Lung cancer

292

74

1.11

(0.86–1.44)

318

69

0.93

(0.71–1.21)

Kidney cancer

69

28

1.72

(1.10–2.68)*

68

17

0.99

(0.57–1.71)

Bladder cancer

80

24

1.24

(0.78–1.97)

87

24

1.20

(0.75–1.90)

Uterine and corpus cancerb

43

14

1.28

(0.69–2.37)

26

11

1.82

(0.87–3.78)

Cervical cancerb

62

10

0.74

(0.38–1.46)

62

11

0.81

(0.42–1.56)

Ovarian cancerb

27

15

2.31

(1.21–4.39)*

10

8

5.15

(1.98–13.4)

Prostate cancerc

134

30

0.95

(0.64–1.42)

136

24

0.81

(0.52–1.27)

Breast cancerb

256

74

1.25

(0.96–1.62)

197

46

1.08

(0.78–1.50)

Melanoma

14

0

--

--

12

2

0.78

(0.17–3.60)

Skin cancer

37

15

1.46

(0.79–2.69)

37

11

1.09

(0.54–2.17)

Non-Hodgkin’s lymphoma

45

22

2.10

(1.25–3.52)

45

20

2.30

(1.34–3.96)

Myeloma

12

2

0.93

(0.20–4.25)

13

3

1.15

(0.32–4.20)

Leukemia

43

15

1.44

(0.79–2.61)

25

7

1.21

(0.51–2.87)

  1. *p < 0.05, p < 0.001, p < 0.0001
  2. aAdjusted for sex, age, geographical region, occupation, level of urbanization, monthly income, the presence of comorbidities, and number of outpatient visits
  3. bWomen only
  4. cMen only