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Table 3 Mean ± SD of protein concentrations of activin-A, activin-B, activin-AB and follistatin in serum and colon tissue homogenates by ELISA

From: Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer

  Normal group S-AOM group L-AOM group
Activin-A (pg/mL) Tissue 388.8 ± 61.7 586.4 ± 72.6b 862.3 ± 210.2b,d
Serum 266.5 ± 41.7 472.4 ± 63.3b 614.8 ± 111.4b,c
Activin-B (pg/mL) Tissue 337.8 ± 68 298.1 ± 54.7 315.2 ± 47.3
Serum 180.4 ± 43.3 191.2 ± 32.8 213.9 ± 56.5
Activin-AB (pg/mL) Tissue 277.4 ± 34.2 154.7 ± 41.4a 83.4 ± 24.2b,c
Serum 181.7 ± 62.8 172.9 ± 40.9 202.2 ± 77.8
Follistatin (ng/mL) Tissue 5.6 ± 1.8 15.2 ± 3.9b 38.01 ± 6.2b,d
Serum 3.83 ± 1.1 7.4 ± 2.3b 11.2 ± 2.9b,c
  1. (aP < 0.05 compared with control; bP < 0.01 compared with control, cP < 0.05 compared with S-AOM group and dP < 0.01 compared with S-AOM group)