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Table 3 Mean ± SD of protein concentrations of activin-A, activin-B, activin-AB and follistatin in serum and colon tissue homogenates by ELISA

From: Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer

 

Normal group

S-AOM group

L-AOM group

Activin-A (pg/mL)

Tissue

388.8 ± 61.7

586.4 ± 72.6b

862.3 ± 210.2b,d

Serum

266.5 ± 41.7

472.4 ± 63.3b

614.8 ± 111.4b,c

Activin-B (pg/mL)

Tissue

337.8 ± 68

298.1 ± 54.7

315.2 ± 47.3

Serum

180.4 ± 43.3

191.2 ± 32.8

213.9 ± 56.5

Activin-AB (pg/mL)

Tissue

277.4 ± 34.2

154.7 ± 41.4a

83.4 ± 24.2b,c

Serum

181.7 ± 62.8

172.9 ± 40.9

202.2 ± 77.8

Follistatin (ng/mL)

Tissue

5.6 ± 1.8

15.2 ± 3.9b

38.01 ± 6.2b,d

Serum

3.83 ± 1.1

7.4 ± 2.3b

11.2 ± 2.9b,c

  1. (aP < 0.05 compared with control; bP < 0.01 compared with control, cP < 0.05 compared with S-AOM group and dP < 0.01 compared with S-AOM group)