Fig. 5
From: Secreted Frizzled-Related Protein 2 (sFRP2) promotes osteosarcoma invasion and metastatic potential
sFRP2 promotes OS metastasis, but not primary tumor growth, in vivo. a Representative images of primary implanted tumors and tumor mass (in grams) sacrificed at 8Â weeks for control RF43 and sFRP2/RF43 cells. b Representative gross images of lungs from RF43 control and sFRP2/RF43 injected mice (left panels, black arrows indicate macroscopic lung lesions). Quantification of lung nodules shown in graph (right panel) (c). Representative H&E images from lungs of RF43 control and sFRP2/RF43 injected mice. Black arrow indicates metastatic lung nodule