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Table 1 Patients clinical data

From: Autophagy is associated with chemoresistance in neuroblastoma

Variable LC3B Beclin-1
  No (%) No % Mean
Intensity
p No % Mean
Intensity
p
All patients 184 148 80 0.83   153 83 1.03  
Age
 Median (Range), months 26 (0–151)         
 <365 days 88 (48) 73 83 0.92   70 80 0.83  
 ≥365 days 96 (52) 74 77 0.75 ns 84 87.5 1.25 <0.01
Stage
 1 53 (29) 47 88 0.6 ns 48 90 1.30 ns
 2 35 (19) 25 71 0.64   27 77 0.8  
 3 23 (12) 21 91 0.94   20 86 1.14  
 4 58 (32) 52 89 1.12   47 81 0.97  
 4S 15 (8) 11 73 0.34 0.02 11 73 0.72 ns
MYCN status
 Amplified 14 (10) 13 87 0.81   11 73 0.87  
 Non Amplified 127 (90) 103 81 0.50 ns 105 82 0.43 ns
 Unknown 43         
Type of NB
 Standard 149 (81) 133 89 0.96   126 84 1.19  
 Mass screening 35 (19) 29 82 0.8 ns 27 77 0.46 <0.001
Type of samples
 Primary tumors 184 148 80 0.83   153 83 1.03  
 Metastases 47 41 87 0.78 ns 37 79 0.69 <0.01