Fig. 7

Let-7a was inversely related with Wnt1 and indicated better clinical prognosis. a. Representative images of immunohistochemical staining for β-catenin in tissues of different clinical stages. b. d. Quantification of relative immunostaining intensity of β-catenin, StagingIhad the least expression of β-catenin. c. Quantification of let-7a in HCC tissues and adjacent normal tissues, the relative quantity was calculated by 2^-ΔΔCt, with U6 acting as the internal reference. The statistical analysis was performed using T test. d. Wnt1 mRNA expression in tissues from 20 patients were tested, and there is inverse correlationship between let-7a miRNA and Wnt1 mRNA was found, Pearson = −0.722, p < 0.01