Variable | MACC1 | P value | ALDH1 | P value | ||
---|---|---|---|---|---|---|
negative | positive | negative | positive | |||
Tissue | <0.001 | <0.001 | ||||
Normal | 217 | 23 | 210 | 30 | ||
NSCLC | 86 | 154 | 106 | 134 | ||
Gender | 0.341 | 0.854 | ||||
Male | 54 | 106 | 70 | 90 | ||
Female | 32 | 48 | 36 | 44 | ||
Age (years) | 0.622 | 0.918 | ||||
< 60 | 38 | 63 | 45 | 56 | ||
≥ 60 | 48 | 91 | 61 | 78 | ||
Gross type | 0.575 | 0.677 | ||||
Central | 60 | 102 | 70 | 92 | ||
Peripheral | 26 | 52 | 36 | 42 | ||
Histological type | 0.505 | 0.035 | ||||
Squamous cell carcinoma | 55 | 105 | 63 | 97 | ||
Adenocarcinoma | 31 | 49 | 43 | 37 | ||
Diameter of tumor | 0.490 | 0.596 | ||||
< 3.0 cm | 17 | 25 | 17 | 25 | ||
≥ 3.0 cm | 69 | 129 | 89 | 109 | ||
Grade of tumor | 0.015 | <0.001 | ||||
Well | 19 | 14 | 26 | 7 | ||
Moderately | 53 | 104 | 70 | 87 | ||
Poorly | 14 | 36 | 10 | 40 | ||
Lymph node metastasis | <0.001 | <0.001 | ||||
No | 56 | 60 | 84 | 32 | ||
Yes | 30 | 94 | 22 | 102 | ||
TNM stage | 0.001 | <0.001 | ||||
I | 18 | 14 | 25 | 7 | ||
II | 38 | 50 | 60 | 28 | ||
III | 30 | 90 | 21 | 99 | ||
ALDH1 expression | <0.001* | |||||
Negative | 59 | 47 | ||||
Positive | 27 | 107 |