Metastasis-associated in colon cancer-1 and aldehyde dehydrogenase 1 are metastatic and prognostic biomarker for non-small cell lung cancer

Table 1 Correlation between the expression of MACC1 and ALDH1 and clinicopathololgical characteristics in NSCLC

Variable	MACC1		P value	ALDH1		P value
Variable	negative	positive	P value	negative	positive	P value
Tissue			<0.001			<0.001
Normal	217	23		210	30
NSCLC	86	154		106	134
Gender			0.341			0.854
Male	54	106		70	90
Female	32	48		36	44
Age (years)			0.622			0.918
< 60	38	63		45	56
≥ 60	48	91		61	78
Gross type			0.575			0.677
Central	60	102		70	92
Peripheral	26	52		36	42
Histological type			0.505			0.035
Squamous cell carcinoma	55	105		63	97
Adenocarcinoma	31	49		43	37
Diameter of tumor			0.490			0.596
< 3.0 cm	17	25		17	25
≥ 3.0 cm	69	129		89	109
Grade of tumor			0.015			<0.001
Well	19	14		26	7
Moderately	53	104		70	87
Poorly	14	36		10	40
Lymph node metastasis			<0.001			<0.001
No	56	60		84	32
Yes	30	94		22	102
TNM stage			0.001			<0.001
I	18	14		25	7
II	38	50		60	28
III	30	90		21	99
ALDH1 expression			<0.001*
Negative	59	47
Positive	27	107

ISSN: 1471-2407