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Table 2 Patient characteristics analyzed in our study (n = 61)

From: Frequency of EGFR T790M mutation and multimutational profiles of rebiopsy samples from non-small cell lung cancer developing acquired resistance to EGFR tyrosine kinase inhibitors in Japanese patients

Age, year

 Median

64

 Range

39–84

Sex, n (%)

 Female

44 (72%)

 Male

17 (28%)

Smoking history, n (%)

 Never

44 (72%)

 Former/Current

17 (28%)

ECOG performance status, n (%)

 0–1

52 (85%)

 2–4

9 (15%)

Pretreatment EGFR status, n (%)

 Exon19 deletion

37 (61%)

 Exon21 L858R

19 (31%)

 Other

5 (8%)

EGFR TKI, n (%)

 Gefitinib

49 (80%)

 Erlotinib

7 (12%)

 2nd generation

5 (8%)

  1. Abbreviations: ECOG eastern cooperative oncology group, EGFR epidermal growth factor receptor, TKI tyrosine kinase inhibitor