Fig. 6

Growth hormone enhances lung nodule formation in C57/B6 mice. B16F10 cells (6 × 10⁴ cells) were injected into the femoral vein of C57/B6 mice. The mice were subcutaneously injected with GH (a) or prolactin (b) (5 mg/kg, twice/week, respectively). The lung nodules were photographed and counted three weeks later. Results showed an increase in the number of lung nodules in C57/B6 mice following GH administration and there was on difference after prolactin administration. Data are presented as mean ± SEM (n = 11–12 for each group in a; n = 5 for each group in b); *, P < 0.05 compared to the control. Scale bar = 3 mm