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Table 3 Adjusted mean RR estimates of prostate cancer morbidity or mortality for different categories of drinkers compared with abstainers (N = 27 studies and 126 risk estimates)

From: Is alcohol consumption a risk factor for prostate cancer? A systematic review and meta–analysis

Drinking categories N/na Weighted Mean RRb Partially adjusted mean RRc Fully adjusted mean RRd
RR & 95 % CI t–test P RR & 95 % CI t–test P RR & 95 % CI t–test P
Abstainer   1.00    1.00    1.00   
Former drinker 7/13 1.14 0.99 – 1.30 0.0642 1.12 0.98 – 1.29 0.0990 1.10 0.97 – 1.25 0.1348
Occasional (<1.30 g/day) 6/7 0.97 0.86 – 1.10 0.6126 0.96 0.85 – 1.08 0.5265 0.95 0.85 – 1.06 0.3263
Low volume (1.30– < 25 g/day) 27/62 1.07 1.04 – 1.10 0.0001 1.08 1.05 – 1.12 0.0001 1.08 1.04 – 1.11 0.0001
Medium volume (25– < 45 g/day) 18/20 1.06 1.02 – 1.11 0.0068 1.08 1.03 – 1.13 0.0023 1.07 1.02 – 1.12 0.0041
High volume (45– < 65 g/day) 10/11 1.15 1.08 – 1.22 0.0001 1.17 1.09 – 1.25 0.0001 1.14 1.08 – 1.22 0.0001
Higher volume (65+ g/day) 9/13 1.18 1.09 – 1.27 0.0001 1.20 1.11 – 1.29 0.0001 1.18 1.10 – 1.27 0.0001
Any drinking 27/126 1.08 1.04 – 1.12 0.0039 1.10 1.02 – 1.18 0.0214 1.08 1.01 – 1.17 0.0364
  1. Note: a N = Number of studies and n = Number of risk estimates. bWeighted using the inverse of variance of natural log–RR. cWeighted RR estimates adjusted for both former and occasional drinker biases. dWeighted RR estimates adjusted for between–study variation, both former and occasional drinker biases, US/non–US study and control for smoking status in individual studies