BMC Cancer

Table 2 The expression of HER1 - HER4 in different subgroups

From: The prognostic significance of human epidermal growth factor receptor family protein expression in operable pancreatic cancer

	HER1			HER2			HER3			HER4
	− n	+ n	P	− n	+ n	P	− n	+ n	P	− n	+ n	P
Sex			0.027			0.258			0.564			0.164
Male	12	16		13	15		21	7		12	16
Female	29	13		15	27		32	10		12	30
Age			0.663			0.519			0.446			0.139
< 60 y	19	15		14	20		25	9		9	25
≥ 60 y	22	14		14	22		28	8		15	21
Tumor family history			0.338			0.671			0.237			0.563
Yes	2	3		2	3		5	0		2	3
No	39	26		26	39		48	17		22	43
Smoking history			0.094			0.579			0.389			0.026
Yes	5	8		5	8		9	4		8	5
No	36	21		23	34		44	13		16	41
Drinking history			0.310			0.085			0.220			0.042
Yes	13	4		5	2		4	3		5	2
No	28	25		23	40		49	14		19	44
Tumor location			0.856			0.127			0.589			0.409
Head	26	19		15	30		35	10		17	28
Body + tail	15	10		13	12		18	7		7	18
Pathology types			0.138			0.233			0.113			0.014
Adenocarcinoma	28	24		19	33		37	15		22	30
Non-adenocarcinoma	13	5		9	9		16	2		2	16
Differentiation			0.026			0.167			0.144			0.570
Lower	6	11		9	8		15	2		6	11
Higher	35	18		19	34		38	15		18	35
T stage			0.663			0.330			0.164			0.017
T1 + T2	19	15		15	19		28	6		7	27
T3 + T4	22	14		13	23		25	11		17	19
N stage			0.566			0.480			0.496			0.329
N0	23	16		15	24		29	10		12	27
N1	18	13		13	18		24	7		12	19
M stage			0.273			0.598			0.091			0.269
M0	35	27		25	37		49	13		20	42
M1	6	2		3	5		4	4		4	4
CA199			0.467			0.020			0.332			0.480
< 1200 U/ml	34	23		19	38		42	15		19	38
> 1200 U/ml	7	6		9	4		11	2		5	8

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