Skip to main content

Table 2 The expression of HER1 - HER4 in different subgroups

From: The prognostic significance of human epidermal growth factor receptor family protein expression in operable pancreatic cancer

  HER1 HER2 HER3 HER4

n
+
n
P
n
+
n
P
n
+
n
P
n
+
n
P
Sex    0.027    0.258    0.564    0.164
 Male 12 16   13 15   21 7   12 16  
 Female 29 13   15 27   32 10   12 30  
Age    0.663    0.519    0.446    0.139
 < 60 y 19 15   14 20   25 9   9 25  
 ≥ 60 y 22 14   14 22   28 8   15 21  
Tumor family history    0.338    0.671    0.237    0.563
 Yes 2 3   2 3   5 0   2 3  
 No 39 26   26 39   48 17   22 43  
Smoking history    0.094    0.579    0.389    0.026
 Yes 5 8   5 8   9 4   8 5  
 No 36 21   23 34   44 13   16 41  
Drinking history    0.310    0.085    0.220    0.042
 Yes 13 4   5 2   4 3   5 2  
 No 28 25   23 40   49 14   19 44  
Tumor location    0.856    0.127    0.589    0.409
 Head 26 19   15 30   35 10   17 28  
 Body + tail 15 10   13 12   18 7   7 18  
Pathology types    0.138    0.233    0.113    0.014
 Adenocarcinoma 28 24   19 33   37 15   22 30  
 Non-adenocarcinoma 13 5   9 9   16 2   2 16  
Differentiation    0.026    0.167    0.144    0.570
 Lower 6 11   9 8   15 2   6 11  
 Higher 35 18   19 34   38 15   18 35  
T stage    0.663    0.330    0.164    0.017
 T1 + T2 19 15   15 19   28 6   7 27  
 T3 + T4 22 14   13 23   25 11   17 19  
N stage    0.566    0.480    0.496    0.329
 N0 23 16   15 24   29 10   12 27  
 N1 18 13   13 18   24 7   12 19  
M stage    0.273    0.598    0.091    0.269
 M0 35 27   25 37   49 13   20 42  
 M1 6 2   3 5   4 4   4 4  
CA199    0.467    0.020    0.332    0.480
 < 1200 U/ml 34 23   19 38   42 15   19 38  
 > 1200 U/ml 7 6   9 4   11 2   5 8