Table 2 Characteristics of the ideal response biomarker
From: Response biomarkers: re-envisioning the approach to tailoring drug therapy for cancer
Sufficiently sensitive to detect even minor responses that induce disease stabilization. |
Specific. Its absence accurately reflects chemoresistance. |
Appears rapidly as a result of a response to therapy. |
Agnostic to class of antineoplastic drugs. |
Applicable to all tumor types. |
Easy to measure, amenable to high-throughput testing. |
Inexpensive. |
Measurement is convenient to the patient and physician. |