Fig. 1From: Response biomarkers: re-envisioning the approach to tailoring drug therapy for cancerThe drug development pipeline for cancer. a Number of drugs approved each year by the FDA for the treatment of cancer, since 1999. Figure is derived from the annual briefs on New Molecular Entity and New biologic Approvals [74]. b Probability of success in advancing a proposed therapeutic compound from phase 1 clinical trials to FDA approval. Data are derived from Hay et al. [75]Back to article page