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Table 1 E6/E7 mRNA detection according to cytology results

From: Assessment of human papillomavirus E6/E7 oncogene expression as cervical disease biomarker

    E6/E7mRNA expression (n/%)
Cytology result mRNA positive mRNA negative
mRNA once tested samples
(N = 77)
T0 Normal 19/48.72 20/51.28
ASCUS + LSIL 25/89.28 3/10.72
HSIL 10/100.00 0/0
T2 Normal 13/40.62 19/59.38
ASCUS + LSIL 19/82.60 4/17.40
HSIL 22/100.00 0/0.00
mRNA twice tested samples
(N = 23)
T0 Normal 7/63.63 4/36.37
ASCUS + LSIL 7/77.77 2/22.23
HSIL 3/100.00 0/0.00
T2 Normal 4/44.44 5/55.56
ASCUS + LSIL 7/70.00 3/30.00
HSIL 4/100.00 0/0.00
  1. T0 corresponds to the time when the sample was collected and mRNA was analysed and T2 corresponds to next 2 years pathology progressions based on cytological results. Cytology results were divided into three groups: 1) normal (no lesion), 2) Atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intraepithelial lesion (LSIL) and 3) High-grade squamous intraepithelial lesion (HSIL)