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Table 3 Data extract of SAA expression in control and cancer patients

From: Increased serum amyloid A as potential diagnostic marker for lung cancer: a meta-analysis based on nine studies

Author Concentration of SAA (Mean ± standard deviation) Positive /all (N) Diagnostic test (2 × 2 table)
Control All cancer cases LAC LSCC SCLC Control Lung cancer TP FP FN TN
Benson MD [12] 135 ± 31 1880 ± 251 1460 ± 494 1923 ± 317 1118 ± 317 14/50 45/50 45 14 5 36
Howard BA [13] 34.1 286 NA NA NA 1/15 15/19 15 1 4 14
Khan N [14] 43.8 ± 9.65 83.5 ± 19.5 NA NA NA 4/25 14/25 14 4 11 21
Dai S [16] 2.15 ± 0.73 18.48 ± 21.22 NA NA NA NA NA NA NA NA NA
Liu DH [17] 2.1 ± 0.7 19.3 ± 20.6 15.1 ± 22.4 34.3 ± 20.2 25.7 ± 26 0/82 95/193 95 0 98 82
Cho WC [15] 0.109 ± 0.033 1.872 ± 0.212 NA NA NA NA NA NA NA NA NA
  17.06 ± 2.55 710.77 ± 250.42          
Sung HJ [4] 13.89 ± 37.18 190.49 ± 234.70 190.49 ± 134.70 302.76 ± 305.21 116.38 ± 81.13 7/140 90/170 90 7 80 133
Dowling P [18] 9.8 NA 141.6 54.8 172.2 NA NA NA NA NA NA
Kanoh Y [9] 8.2 ± 10.55 158 ± 448.7 NA NA NA 0/13 24/24 24 0 0 13
  1. N, cases; NA, unavailable; true positive; LAC lung adenocarcinoma; LSCC lung squamous cell carcinoma; SCLC small cell lung cancer; FP false positive; FN false negative; TN true negative