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Table 1 Search strategy for Medline and Embase (1 March 2015)

From: Temporal trends in the risk of developing multiple primary cancers: a systematic review

Approach 1
Search strategy using MeSH terms in Medline
No. Search
1 “Neoplasms, Multiple Primary/epidemiology”[Mesh] OR "Neoplasms, Multiple Primary/prevention and control"[Mesh] OR "Neoplasms, Second Primary/epidemiology"[Mesh] OR "Neoplasms, Second Primary/prevention and control"[Mesh] AND "Time Factors"[Mesh]
N = 657
2 Limits: adults
N = 498
Search strategy using keywords in Medline
1 multiple primary cancer*[Title/Abstract]
N = 576
2 multiple primary malignanc*[Title/Abstract]
N = 208
3 multiple primary tumo*[Title/Abstract]
N = 386
4 multiple primary carcinoma*[Title/Abstract]
N = 130
5 second cancer*[Title/Abstract]
N = 1,272
6 second malignanc*[Title/Abstract]
N = 1,622
7 second tumo*[Title/Abstract]
N = 951
8 second carcinoma*[Title/Abstract]
N = 82
9 #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8
N = 4,801
10 time[Title/Abstract] OR period*[Title/Abstract] OR interval*[Title/Abstract] OR calendar year*[Title/Abstract]
N = 3,401,312
11 population[Title/Abstract]
N = 936,431
12 risk[Title/Abstract]
N = 1,328,908
13 #9 AND #10 AND #11 AND #12
N = 302
17 Limits: adult: 19+ years
N = 236
Search strategy using keywords in Embase
1 Multiple AND primary AND (‘cancer’/exp OR cancer) OR multiple AND primary AND malignanc* OR multiple AND primary AND tumor* OR multiple AND primary AND carcinoma* OR second AND (‘cancer’/exp OR cancer) OR second AND malignanc* OR second AND tumor* OR second carcinoma*
N = 236,978
2 Time AND period* OR time AND interval* OR calendar AND year*
N = 691,550
2 #1 AND #2 AND population AND risk AND [embase]/lim
N = 457
Approach 2
Search strategy using MeSH terms in Medline
No. Search
1 "Neoplasms, Multiple Primary"[Mesh] OR "Neoplasms, Multiple Primary"[Mesh] OR "Neoplasms, Second Primary"[Mesh] OR "Neoplasms, Second Primary"[Mesh] AND "Risk Assessment"[Mesh]
N = 613
2 Limits: adults
N = 455
Search strategy using keywords in Medline
1 multiple primary cancer*[Title/Abstract]
2 multiple primary malignanc*[Title/Abstract]
3 multiple primary tumo*[Title/Abstract]
4 multiple primary carcinoma*[Title/Abstract]
5 multiple cancer*[Title/Abstract]
6 multiple malignanc*[Title/Abstract]
7 multiple tumo*[Title/Abstract]
8 multiple carcinoma*[Title/Abstract]
9 second primary cancer*[Title/Abstract]
10 second primary malignanc*[Title/Abstract]
11 second primary tumo*[Title/Abstract]
12 second primary carcinoma*[Title/Abstract]
13 second primary cancer*[Title/Abstract]
14 second primary malignanc*[Title/Abstract]
15 second primary tumo*[Title/Abstract]
16 second primary carcinoma*[Title/Abstract]
17 #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16
N = 12,841
18 time OR period* OR year*
N = 5,764,460
19 population-based[Title/Abstract]
20 risk[Title/Abstract]
21 #17 AND #18 AND #19 AND #20
N = 232
17 Limits: adult: 19+ years
N = 186